Order soma 37 WALLACE 2001 SOMA Elgin

Rats exposed to order soma 37 WALLACE 2001 SOMA Elgin meprobamate uteroshowed disorders that persists into adulthood. For children exposed in utero to meprobamate, a study found no negative effects on mental development or motor ouQI. Carisoprodol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. No information on the effects of carisoprodol in the mother and fetus during labor. Very limited data in humans indicate that carisoprodol is present in breast milk and may reach concentrations two to four times the levels of maternal plasma. In one case, an infant received approximately 46% of the maternal daily dose through breast milk and experienced no adverse effects. However, milk production was inadequate and that the baby was supplemented with formula. In studies of lactation in mice, the survival of women and newborn pup weight order soma 37 WALLACE 2001 SOMA Elgin at weaning was reduced. These data suggest that maternal use of carisoprodol may lead to the reduction of infant feeding or less effective (because lasedación) order soma 37 WALLACE 2001 SOMA Elgin and / or decreased milk production. Caution should be exercised when administered to a nursing mother carisoprodol. The efficacy, safety and pharmacokinetics of carisoprodol in pediatric patients under 16 years have not been established. The efficacy, safety and pharmacokinetics of carisoprodol in patients over 65 have not been established. The safety order soma 37 WALLACE 2001 SOMA Elgin and pharmacokinetics of carisoprodol in patients with renal impairment have not been evaluated.

Since carisoprodol is excreted by the kidneys, caution should be exercised if carisoprodol order soma 37 WALLACE 2001 SOMA Elgin is administered to patients with renal failure.

Carisoprodol is dialyzable by hemodialysis and peritoneal dialysis. The safety and pharmacokinetics of carisoprodol in patients with hepatic impairment have not been evaluated. Since carisoprodol is metabolized in the liver, caution should be exercised if carisoprodol is administered to patients with liver failure. Patients with reduced activity CYP2C19 have higher exposure to carisoprodol. Therefore, caution should be exercised in the administration of carisoprodol in these patients [see Clinical Pharmacology (order soma 37 WALLACE 2001 SOMA Elgin 12.3)]. [See Warnings and Precautions (5.2)] carisoprodol overdose generally produce CNS depression.

Death, coma, respiratory depression, hypotension, convulsions, delirium, hallucinations, dystonic reactions, nystagmus, blurred vision, mydriasis, euphoria, muscular incoordination, rigidity and / or headache have been reported with carisoprodol overdose. Many carisoprodol overdose order soma 37 WALLACE 2001 SOMA Elgin took place as part of a multiple drug overdose (including drug abuse, illicit drugs and alcohol). The effects of an overdose of CNS depressants and carisoprodol (eg, alcohol, benzodiazepines, opioids, tricyclic antidepressants) may be additive, even if a drug is taken at the recommended dose. Fatal accidental and non accidental overdose of carisoprodol have been reported alone or in combination with other CNS depressants.